Buy 4-AcO-DMT (or psilacetin) is a semi-synthetic tryptamine closely related to the psychedelic mushroom molecules psilocin and psilocybin. 4-AcO-DMT is widely known as “synthetic mushrooms.” Like psilocybin, it appears that the body metabolizes 4-AcO-DMT into psilocin
acetoxy- N, N- Dimethyltryptamine
4-Aco-DMT For Sale
Firstly Very little data exist on the receptor binding and metabolism of 4-AcO-DMT. Like psilocybin, it’s thought to be a prodrug of psilocin—in this case, deacetylated to psilocin during the first-pass metabolism by the stomach and liver. On that basis, we can safely assume that 4-AcO-DMT has roughly the exact mechanism of action—primarily activating (like many other psychedelics) the 5-HT2A serotonin receptors.
But some think it may be more than just a prodrug of psilocin. Anecdotal reports of near-immediate psychoactivity when injected or smoked (i.e., bypassing the first-pass metabolism) suggest it may have its pharmacodynamic profile. This could also account for perceived differences between psilocybin and 4-AcO-DMT when taken orally. That said, it’s worth noting that naturally occurring psilocybin tends to be accompanied in mushrooms by other alkaloids with presumed effects, such as baeocystin and norbaeocystin. Neither of these are present in 4-AcO-DMT powders.